Detection of precancerous gastric lesions and gastric cancer外文文献资料.docxVIP

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Detection of precancerous gastric lesions and gastric cancer外文文献资料.docx

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Amal H# Amal H# ef a/. Gut 2015;0:1-8. doi:10.1136/gutjnl-2014-308536 Amal H Amal Hr et at. Gut 2015;0:1-8. doi:10.1136/gutjnl-2014-308536 BMJ BMJ Amal Hf et al. Gut 2015;0:1-8. doi:10.1136/gutjnl-2014-308536 m ORIGINAL ARTICLE Detection of precancerous gastric lesions and gastric cancer through exhaled breath Haitham Amal,1 Marcis Leja,2,34 Konrads Funka,2,3,4 Roberts Skapars,2,3 Armands Sivins,2,3 Guntis Ancans,2,3 Inta Liepniece-Karele,2,3,5 llze Kikuste,2,4 leva Lasina,2 Hossam Haick1 ? Additional material is published online only. To view please visit the journal online (hTtp:///10.1136/ gutjnl-2014-308536). ? Additional material is published online only. To view please visit the journal online (hTtp:///10.1136/ gutjnl-2014-308536). 1 Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion—Israel Institute of Technology, Haifa, Israel faculty of Medicine, University of Latvia, Riga, Latvia ^Department of Research, Riga East University Hospital, Riga, Latvia ^Digestive Diseases Centre GASTRO, Riga, Latvia Academic Histology laboratory, Riga, Latvia Correspondence to Professor Hossam Haick, Department of Chemical Engineering and Russell Berrie Nanotechnology Institute, Technion—Israel Institute of Technology, Haifa 3200003, Israel; HYPERLINK mailto:hhossam@technion.ac.il hhossam@technion.ac.il HA and ML contributed Received 29 September 2014 Revised 25 January 2015 Accepted 7 February 2015 To cite: Amal H, Leja M, Funka K, et al. Gut Published Online First: [please include Day Month Year) doi:10.1136/gutjnl- 2014-308536 ABSTRACT Objectives Timely detection of gastric cancer (GC) and the related precancerous lesions could provide a tool for decreasing both cancer mortality and incidence. Design 968 breath samples were collected from 484 patients (including 99 with GC) for two different analyses. The first sample was analysed by gas chromatography linked to mass spectrometry (GCMS) while applying t test with multiple corrections (