新生儿缺氧缺血性脑病Hypoxic-IschemicEncephalopathy(HIE).pptVIP

新生儿缺氧缺血性脑病Hypoxic-Ischemic Encephalopathy(HIE) Department of pediatrics 陈平洋 Purpose To be familiar with etiology, Mechanism and prevention To master clinical manifestation, diagnosis and treatment To understand the prognosis Summary HIE（缺氧缺血性脑病）is caused by perinatal asphyxia（围生期的窒息） HIE is a disease primarily of the term infant Etiology and Mechanism（病因与发病机制） Selective vulnerabilities（选择易损性） Occur in selected areas of the brain stem, （脑干）thalamencephalon（丘脑）and cerebellum（小脑） where metabolism is vigorous and which are most sensitive to hypoxicisc