年产6000吨植酸酶发酵工厂设计.doc

山东科技大学毕业设计说明书 PAGE 山东科技大学 本科生毕业设计说明书 题 目：年产6000吨植酸酶发酵工厂设计 学生姓名：李桂鼎 学 号：0901111212 专 业：生物工程 班 级：09—2班 指导教师：韩秋霞 山东科技大学毕业设计说明书 PAGE 82 年产6000吨植酸酶制剂生产工艺段设计 摘要 本次毕业设计的任务是年产6000吨植酸酶制剂生产工厂设计。 在现代食品工业中, 酶的应用几乎涉及到食品加工的各个领域。随着酶制剂日益广泛的应用,经济效益显著。植酸酶是一类催化植酸（肌醇六磷酸酯）及植酸盐水解成无机磷和肌醇的酶的总称。植酸酶不但可以使单胃动物利用有机磷，还可减少磷的排出，减轻环境污染，所以植酸酶引起众多科研工作者的广泛关注，植酸酶生产的具体工艺流程，通过物料衡算确定需要立方米发酵罐台和立方米种子罐台，在此基础上得出发酵工段所需要的各种原料量，通过能量衡算确定水、无菌空气和蒸汽等的消耗量。然后对主要设备进行计算和选型，得出发酵罐、种子罐及通用设备、非标准设备等的结构尺寸、冷却装置、传动装置，根据工艺要求确定罐的附属设备和辅助设备以及发酵过程中的优化控制，然后进行植酸酶制剂活性测定。最后设计了发酵工厂的车间布局，提出了相应的公用工程、安全卫生与环境保护等辅助工艺。根据计算结果，设计了六张图纸，分别为发酵罐装配图、种子罐装配图、工艺管道及仪表流程图、厂房车间布置图、物料流程图和设备一览表。 关键词：碱性蛋白酶；发酵；工艺设计 The graduation projects mission is to make a production plant design, whose annual output is 6,000 tons of phytase preparation. Abstract In modern food industry, enzymes are used involving almost all areas of food processing. With the increasingly widespread application of enzymes, it has significant economic benefits. Phytase is a class of enzyme that can catalyze phytate (inositol hexaphosphate) and phytic acid salt hydrolyzing into inorganic phosphorus and inositol. Phytase not only make monogastric animals can use of organic phosphorus, but also can reduce the discharge of phosphorus and the environmental pollution, so phytase caused widespread concern of many researchers. Specific phytase production process, by material balance determine demand an m3 of fermenters one and an m3 of seed tankone, deriving all the required material of fermentation section based on that. Determined through the energy balance of water, sterile air and steam consumption. Then calculate and select the main device, obtaining the structure,the size, the cooling device and transmission device of the fermenter ,seed tank, general equipment and non-standard equipment. According to the technical requirements to determine tanks’ ancillary equipment, auxiliary equipment and optimized control in the fermentation process, then make preparations phytase activit