Tumor Viruses课件.pptVIP

RNA Tumor Viruses Viral Oncogene V-onc Cellular Proto-oncogene C-onc 精品文档 RNA Tumor Viruses Proto-oncogene A cellular (host) gene that is homologous with a similar gene that is found in a transforming virus A cellular oncogene can only induce transformation after mutation some other change in the cell’s genome 精品文档 RNA Tumor Viruses Viral RNA genome Reverse transcriptase (Virus-encoded) Viral DNA genome (integrated) DNA-dependent RNA polymerase (Host RNA pol II) Viral genomic RNA Splicing (Host splicing enzymes) messenger RNA viral protein