课件：COS诊治进展.ppt

二甲双胍开始时有恶心、胀满、气胀和腹泻，可致服药终止； 最严重并发症是乳酸性酸中毒，好发于心衰、肝、肾、肺病者，为使用禁忌； 可抑制Vit B12吸收，注意相应缺乏症； GOTT异常患者，谨慎使用胰岛素增敏剂（如Metformin，等） 芳香化酶抑制剂（如Letrozol，等） Fertil Steril 2007, ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group * The treatment of infertile women with polycystic ovary syndrome (PCOS) is surrounded by many controversies. On the basis of the currently available evidence, a group of experts reached a consensus regarding the therapeutic challenges raised in these women. Before any intervention is initiated, preconceptional counseling should be provided emphasizing the importance of lifestyle, espec