棕-3多不饱和脂肪酸抑制小鼠视网膜新生血管的试验研究-眼科杂志.PDF

Int Eye Sci,Vol.18,No.1Jan. 2018摇 摇 http:/ / Tel:029 Email:IJO.2000@163.com ·实验论著 · 棕-3 多不饱和脂肪酸抑制小鼠视网膜新生血管的实验 研究 李摇 琴,黎摇 智,张蝶念,张少维 基金项目:湖北省自然科学基金项目(No.2014CFB214);湖北省 fluorescein angiography on flat - mounted retina. The 卫计委青年人才项目(No郾WJ2017Q039) number of endothelial cell nuclei breaking through the 作者单位:(441021)中国湖北省襄阳市,湖北文理学院附属襄阳 inner linmiting membrane ( ILM) was counted on 市中心医院眼科 hematoxylin and eosin-stained retinal section. The 棕- 作者简介:李琴,硕士,主治医师,研究方向:眼底病。 3PUFAs/ 棕 - 6PUFAs relative amount and ratio was 通讯作者:黎智,博士,副主任医师,眼科副主任,研究方向:眼底 measured by GC-MS inthe retina. A real-time PCR and 病.1103945483@ Western Blot method were used to detect the mRNA, 收稿日期:2017-06-04摇 摇 修回日期:2017-12-06 peroxisome proliferator-avtivated receptor –酌 (RPAR- 酌),vascular endothelial growthfactor-A (VEGF-A) and Regulation of diet containing omega -3 vascularendothelialgrowthfactor receptor2 (VEGFR-2) inthe retina. polyunsaturated fatty acids on retinal 誗RESULTS:Therewas asignificant different inallgroups neovascularization in mice on the relative neovascularization areas and the number of endothelialcell nuclei breaking throu