代谢综合征与无症状脑梗死的相关性研究.docVIP

PAGE \* MERGEFORMAT 1 代谢综合征与无症状脑梗死的相关性研究 乙成成，刘雯雯，张颖秋，王湘芸，郭志军，殷仁富 (200003 上海，第二军医大学附属长征医院贵宾诊疗科) [摘要] 目的 探讨代谢综合征(metabolic syndrome,MS)及其各组分与无症状脑梗死(silent cerebral infarction,SCI)的相关性。 方法 连续收集我科2006年5月至2010年6月健康体检患者959例[男性693例，女性266 例，年龄(49.8±9.1)岁]，根据修订后的中国人代谢综合征诊断标准，将所有患者分为代谢综合征组(443例)和非代谢综合征组(516例)。比较两组患者无症状脑梗死的患病率并采用单因素和多因素Logistic回归法分析代谢综合征及其各组分与无症状脑梗死的相关性。结果 单因素统计分析发现代谢综合征组罹患无症状脑梗死的比例明显高于非代谢综合征组(41.1% VS 27.5%, P＜0.0001请给出具体P值)。多因素Logistic回归分析显示代谢综合征与无症状脑梗死发病明显相关[OR＝1.73,95%CI:1.24～2.41,P＝0.0012请给出具体P值]，在代谢综合征各组分内高血压[OR＝1.40,95%CI: 1.05～1.88, P＝0.0230]、糖尿病[OR＝1.75,95%CI:1.23～2.48,P＝0.0019请给出具体P值]也是无症状脑梗死的独立危险因素，而其他组分无统计学意义。 结论 代谢综合征与无症状脑梗死关系密切，代谢综合征是无症状脑梗死的独立危险因素。 请给出具体P值 请给出具体P值 请给出具体P值 [关键词] 代谢综合征；无症状脑梗死；危险因素 [中图法分类号] R589;R743.9 [文献标识码] A Association Correlation between metabolic syndrome and silent cerebral infarction: a cross-sectional study Yi Chengcheng, Liu Wenwen, Zhang Yingqiu, Wang Xiangyun, Guo Zhijun, Yin Renfu (Department of Diagnosis and Treatment for VIPMedicine, Changzheng Hospital, Second Military Medical University, Shanghai, 200003, China) [Abstract] Objective To determine whether metabolic syndrome (MS) is associated correlated with silent cerebral infarction (SCI). Methods AWe conducted a cross-sectional study which enrolledof 959 health-screening subjects (693 men, and 266 women;, at a mean age,of 49.8±9.1years) who underwent a physical examination in our department from May 2006 to March 2010 was carried out,. These individuals were then divided them into MS group and non-MS group according to .the modified criterion established by the Chinese Medical Association of Diabetes. Prevalence of SCI, was evaluated by the results of MIR scanning. MS was defined by the modified criteria in Chinese. Two groups were compared the prevalence of SCI, and the correlationassociation between MS and SCI were testanalyzed by univariate and multivariate logistic regression analysis. Results This study showed that tThe prevalence of SCI