汕头大学医学院药理学精品课程 Central Stimulants.pptVIP

Central Stimulants GAO Fen-Fei Central Stimulants Classification: Cerebral cortex stimulants: caffeine(咖啡因), theophylline(茶碱), theobromine(可可碱) medulla oblongata(延髓) respiratory center stimulants: nikethamide(尼克刹米), dimefline(二甲弗林;回苏灵) spinal cord(脊髓) stimulants: strychnine(士的宁;马钱子) Nikethamide Metabolite is coramine(可拉明). Mechanism of Action: Direct stimulation of respiratory center Reflex stimulation of respiratory center by stimulating chemoceptor of carotid body(颈动脉体). Clinical Use: Central respiratory depression. Effective in treatment central respiratory depression by morphine, but bad