慢性肾功能衰竭临床分期与血瘀证症状分级量化的相关性分析-中医诊断学专业毕业论文.docxVIP

成都中医药大学硕士学位论文 成都中医药大学硕士学位论文 PAGE PAGE 1 中文摘要 目的：系统对慢性肾功能衰竭（Chronic Renal Failure ，CRF）血瘀证患者不同临 床分期血瘀证症状进行分级量化的研究，旨在探讨 CRF 血瘀证的临床特点，为今后 CRF 的规 范化诊断、治疗提供临床依据。 方法：对 CRF 不同临床分期血瘀证患者血瘀证主症及次症症状分布情况、血瘀证症状 积分情况与诊断性指标内生肌酐清除率的相关性进行分析和研究。 结果：①CRF 血瘀证患者除面色晦暗、肌肤甲错外，其余血瘀证症状与临床分期之间 无统计学差异（P0.05）。② CRF 血瘀证患者面色晦暗症状在肾功能不全代偿期或肾功能不 全失代偿期与肾功能衰竭期或尿毒症期之间具有统计学差异（P0.05）。③ CRF 血瘀证患者 肌肤甲错症状在肾功能不全代偿期或肾功能不全失代偿期与肾功能衰竭期或尿毒症期之间 具有显著统计学差异（P0.01）。 ④ CRF 血瘀证患者不同临床分期之间血瘀证症状积分具有 统计学差异（P0.05）。 ⑤ CRF 血瘀证患者不同临床分期内生肌酐清除率具有显著统计学差 异（P0.01）, 血瘀证症状积分与内生肌酐清除率具有显著统计学差异（P0.01）。 结论：① 慢性肾功能衰竭血瘀证症状中面色晦暗、肌肤甲错多提示处于肾功能衰竭 期或尿毒症期，可考虑肌肤甲错作为慢性肾功能衰竭血瘀证主症症状纳入。②慢性肾功能衰 竭随着疾病进展而瘀血程度加重，其瘀血症状的积分呈进行性加重趋势，提示对慢性肾功能 衰竭临床分期诊断可参考血瘀证症状积分值。③ 慢性肾功能衰竭血瘀证症状积分可代表内 生肌酐清除率水平，一定意义上反映肾功能受损程度，如血瘀证症状越重，内生肌酐清除率 则越低，肾功能受损程度则越重。 关键词：慢性肾功能衰竭；不同临床分期；血瘀证症状；分级量化 Abstract Objective： Systematic research the symptoms’ quantitative classification of blood stasis syndrome which related to patients who suffer from the Chronic Renal Failure with blood stasis syndrome and in different clinical stages. I expect to supply some clinical basis on CRF patients’ standardized diagnosis and therapy in the future, through discussing the clinical features of CRF patients with blood stasis syndrome. Methods: Analyse and research the distribution of blood stasis main and sequence syndrome which related to patients who suffer from the Chronic Renal Failure with blood stasis syndrome and in different clinical stages. Have an analysis of the correlation between scores of blood stasis symptoms and endogenous creatinine clearance rate which is a diagnostic index. Results：① There was no significant difference(P0.05) between symptoms of blood stasis syndrome, except dim complexion, rough skin in CRF blood stasis syndrome patients. ②There were significant differences（P0.05） of symptom dim complexion between blood stasis syndrome patients in the stage of renal insufficiency decompensation and renal failure , decompensated renal insufficiency and renal failure,