辛硫醇-中正大学.PPT

The Limitation of Phosphine Ligand 100 (18) 1.0 0.16 4 1.0 0.48 67 1.0 0.48 92 1.0 0.048 Pd-SR (6) conv% Reaction time (hr) Pdsurf mol % product substrate Cat. 100 (34) 1.0 0.16 6.5 1.0 0.16 80 1.0 0.48 99 1.0 0.08 Pd-SR (6) conv% Reaction time (hr) Pdsurf mol % product substrate Cat. In Hexane In Ethanol Hydrogenation Reactions in Various Solvent Systems (homo.) (hetero.) 42 1.0 0.0050?mg? (9*10-3 mmol) ????? Pd-L-PdCl2 43 1.0 0.0023 mg (9*10-3 mmol) ????? PdCl2(CH3CN)2 conv% Reaction time (hr) mg (Pd(II)含量) substrate Cat. PdCl2(CH3CN)2 vs Pd-L-PdCl2? in Hydrogenation * Synthesis of Pd Nanoparticles Supported Pd(II) Complexes and Catalytic Olefin Hydrogenation and Isomerization Reactions 學生 : 張朝欽 指導老師 : 于淑君 博士 中正大學化學暨生物化學所 High High Low Cat. stabilities Accessible Accessible Difficult Industrialization Easy Easy Difficult Separation ＆ recycle of cat. Mild Harsh Mild Conditions of catalysis High High Low Mechanical strength Low risk Low risk High risk Poisoning of cat. High Low High Selectivity High Low High Activity Easy Difficult Easy Catalyst modification Known Unknown Known Cat. structure Hybrid Heterogeneous Homogenous Characteristics of catalysts Types of Catalysts Homogeneous Catalyst + Cat. S S P Heterogeneous Catalyst + P S S C Hybrid Catalyst + Cat. S S P Solid support The Componemts of Hybrid Catalyst f u n c t i o n a l g r o u p s c a t a l y s t s c o o r d i n a t i o n l i g a n d s Soluble metal complex spacer linker Metal oxide Organicpolymer Silica gel Phosphines Attached to Polymer-Supported Peptides Leadbeater, N. E.; Marco, M. Chem. Rev. 2002, 102, 3217-3274 : polystyrene Bergbreiter, D. E. Chem. Rev. 2002, 102, 3345-3384. Solid/Liquid Separations of Catalysts on Polymers a. Oxidation  b. Metal Leaching Kinzel, E. J. Chem. Soc. Chem. Commun. 1986 1098 Catalyst Design f u n c t i o n a l g r o u p s c a t a l y s t s c o o r d i n a t i o n l i g a n d s Soluble metal complex Nanoparticles with controllable solubility s