Firstrespondertraining培训课件.pptVIP

HHNS : Mortality rate and Pathophysiology Mortality rate : 15%--35% , higher than DKA (5%) Pathophysiology : 1) ? insulin utilization.利用不足 2) ? hepatic gluconeogenesis and glycogenolysis.糖質新生+醣解 3) impaired renal excretion of glucose. HHNS : Nonketotic and Clinical clues Nonketotic : 1) lower Glucagon, growth hormone 2) higher insulin level. 3) prevent lipolysis Clinical clues: 1) weakness, anorexia, fatigue.倦怠 2) usually elderly, abnormalities of mental status, and /or vital signs. 意識改變 Toxicity, 甲醇毒性 毒性來自於代謝引起的甲酸和甲醛 甲酸堆積引起臨床症狀, 甲醛引起視乳突炎和視網膜水腫 症狀： CNS depression, abdominal pai