狼疮静颗粒治疗系统性红斑狼疮肾虚瘀毒证的临床研究-中医内科学专业论文.docxVIP

作者简介姓 作者简介 姓 名： 魏剐 性 别： 男 出生年月： 1977年10月 籍 贯： 江苏太仓 工作学习简历： 1996年9月～1998年7月 南京人学生物科学与技术系96级 1998年9月～2003年7月 南京中医药人学96中医七年制班 RESUME Name：Wei Gang Sex； Male Bn’th：October．1977 Native Place：Jiangsu province DEUCATION 1996～1998 the Biology Depertment of Nanjing Uni versi 1998～2003 Master，Nanji Uni versi of TCM 南京中医药人学硬上学位论文 南京中医药人学硬上学位论文 狼疮静颗粒治疗SLE肾虚瘀毒证的临床研究 Clinical Studies Treating Kidney Vacuity and Stasis Toxin Of SLE wi th Langchuangj i ng Granul Abstract Systemic Lupus Erythematosus(SLE)is the Auto—Immune Di with multi-system involvement and multi—immun0109y abnormaIity caused by factors(genetics．sexormones，environment，medicine，infection，immune reaction and on)．Young suffers from thi disease easilY，it chronic cliaical duration．its morbility is 70．4 in 100 thousand and mortal ity is difficult problems medical field． The research SLE mani that SLE by TCM integrating with medicine good observed the C1inical theraputie which Langehuaagjing granule treated kidney VaCUity and stasiS toxin．and probed into the meehanism the levels cell and C1inical studies Objective：To observe Langchuangjing granule effect the disease activity of SLE patieats．Methods：60 active SLE patients random divided into ICM group(30 cases，treared by TCM integrati wi th medicine)and control group(30 cases，treated medici Be)．and treated six months．We observed the clinical theraputic effect Langchuangjing granu]e treating active SLE．and the effects reducing COrtjcotsteeiods dosage ESR，urine protein，renal function，ANA，SII，一2R．and TNI：一u，C04／CD8 Results：TCM is signjficanLlY the contr01 the total effectiveness rate(93．3％)．improving syndroms(fatigue，dry mouth，1imp lunbus and knees，hair lone)．decreasing ESR，reducing urine protein．improving renal function．adjusting cytokine 1evels(SIL-2R，TNI：一 o)，decreasing dosage of corsteriods and ClX，alleviating side—effects．and decreasing the of SLE relapse(in year)．Conclusion：Langchuangjing gl’anuletreating SI．E of kidne