冠状动脉分叉病变的介入治疗研究进展.DOCVIP

冠状动脉分叉病变的介入治疗研究进展 胡静雯复旦大学上海医学院（上海 200032），葛雷复旦大学附属中山医院心内科 （上海 200032）通信作者：葛均波，E-mail：ge.junbo@，葛均波 NOTEREF _Ref359150628 \h 2 复旦大学上海医学院（上海 200032） 复旦大学附属中山医院心内科 （上海 200032） 通信作者：葛均波，E-mail：ge.junbo@ [摘要] 冠状动脉分叉病变的PCI术极具技术挑战性，其相较非分叉病变有着更不理想的血管造影及临床预后。近期研究显示，主支血管支架植入，必要时分支血管支架植入的技术与常规双支架技术在心源性死亡、心肌梗死、支架内血栓形成、靶血管再次血运重建等方面有着相近的预后。但仍有很多分支血管较大或分支血管开口处显著粥样硬化的病变需要行双支架技术以实现病变的完全覆盖。本文就分叉病变介入治疗研究的最新进展作一综述。 [关键词] 分叉病变；介入治疗；支架；对吻球囊 Research advance in interventional therapy of coronary bifurcation lesions HU Jingwen GE Lei GE Junbo （Shanghai Medical College, Fudan University, Shanghai, 200032, China; Department of cardiology, Zhongshan Hospital, Shanghai, 200032, China） Corresponding author：Ge Junbo, E-mail：ge.junbo@ Summary Percutaneous coronary intervention (PCI) for coronary bifurcation lesions is technically challenging and associated with inferior angiographic and clinical outcomes compared to nonbifurcation lesions. Recent studies have suggested comparable outcomes with a strategy of main branch stenting and provisional stenting of the side branch compared to a 2-stent strategy. However, a significant number of lesions involve large bifurcations or significant atherosclerosis at side branch ostium and require 2 stents for complete coverage. Latest research advances in interventional therapy of coronary bifurcation lesions were reviewed in this article. Key words coronary bifurcation lesions; Percutaneous coronary intervention; stent; final kissing balloon 冠状动脉分叉病变约占经皮冠状动脉介入治疗（PCI）术中所有病变的15-20%左右[[] Meier B, Gruentzig A, King SI, et al. Risk of side branch occlusion during coronary angioplasty[J]. Am J Cardiol, 1984, 53:10-14.][[2] Lefevre T, Louvard Y, Morice MC, et al. Stenting of bifurcation lesions: a rational approach[J]. Interv Cardiol, 2001,1 [] Meier B, Gruentzig A, King SI, et al. Risk of side branch occlusion during coronary angioplasty[J]. Am J Cardiol, 1984, 53:10-14. [2] Lefevre T, Louvard Y, Morice MC, et al. Stenting of bifurcation lesi