临床如何选择B受体阻滞剂-Final-公开课件.pptVIP

BPLTT: Blood Pressure Lowering Treatment Trialist Collaboration ASCOT Anglo-Scandinavian Cardiac Outcomes Trial Reference(s)：(a) J Hypertens 1998;16 Suppl 2:S212 (b) Lancet 2003;361:1149–58 (c) Lancet 2005;366:895–906 Disease：Hypertension Purpose：To assess and compare the effects on nonfatal MI and fatal coronary heart disease of a beta-blocker with or without a diuretic vs a calcium antagonist with or without an ACE inhibitor in hypertensive patients, and of atorvastatinvs placebo in hypertensive patients with dyslipidaemia. Study design: Antihypertensive arm: randomised, parallel-group, 2 ×