胆碱能阻断药-公开课件.pptVIP

Cholinoceptor Blocking Drugs  Classification Base on specific receptor affinities Antimuscarinics Antinicotinics(consist of ganglion-blockers and neuromuscular blockers) Antimuscarinics Antimuscarinics Atropine and its alkaloids semi-synthetic derivative M1 cholinoceptor blocking drugs Pharmacological Effects Glands Sweat, salivary gland secretion are greatly reduced Bronchial secretion decreased Reduction in gastric secretion, especially at doses greater than 1 mg Pharmacological Effects Eye Mydriasis ocular pressure increase cycloplegia Pharmacological Effects Smooth muscle Gastro