将iPS细胞定向分化为胰岛β细胞.doc

iPS细胞定向分化为胰岛β细胞 研究小组成员：刘楠，李辉莹，吴德伟，窦坤，蒋韬，周溦，陈珺，曾扬，杨杨，李磊，吴尚宜，朱翔龙 指导教师：高绍荣博士 Abstract: iPS cells are somatic cell derived pluripotent cells induced by four factors. These cells can give rise to derivatives of all three germ layers. iPS cells have the potential to be differentiated into cell types such as neurons and blood precursors, which has broad implications for the use of stem cells for potential use in therapy. In this project we want to induce iPS cells instead of ES cells to induce pancreatic β cells for transplantation therapy of type I diabetes mellitus which is caused by an autoimmune