Electroacupuncture alleviates the inflammatory response via effects on M1 and M2 macrophages after spinal cord injury 关键词：电针灸过敏性炎症反应对脊髓损伤后M1和M2巨噬细胞的影响.pdf

Downloaded from / on January 25, 2017 - Published by Original paper Electroacupuncture alleviates the inflammatory response via effects on M1 and M2 macrophages after spinal cord injury Jiagui Zhao, Rongyi Zhang, Likui Wang, Yuanhai Li Department of Anesthesiology, ABSTRACT various experimental treatments available The First Affiliated Hospital of Background Macrophages/microglia are for the treatment of SCI; however, no Anhui Medical University, Hefei, Anhui Province, China important effector cells at the site of spinal cord method is completely satisfactory. SCI injury (SCI). M1-type macrophages facilitate triggers a complex local inflammatory Correspondence to innate immunity to remove foreign microbes and response, which is a critical pathophysio- Dr Yuanhai Li, Department of wound debris from the injury site. M2-type logical process that can result in secondary Anesthesiology, The First 3 Affiliated Hospital of Anhui macrophages exhibit tissue repair properties and injury after SCI. Maladaptive inflamma- Medical University, Hefei, Anhui attenuate production of pro-inflammatory tion, specifically macrophage activation, is Province 230022, China; cytokines. Regulation of the polarisation of M1/ likely to be a contributor.4 Macrophages, liyuanhai_1@163.com M2 macrop