幽门螺杆菌对GES-1细胞PI3K2fAKT通路、P21_27WAF1_和Bax的影响和意义.pdfVIP

摘要 Bax的表达，提示H．pylori可能通过激活P21wAFl、Bax而诱导细胞凋亡。 关键词：幽门螺杆菌；P13K／Akt信号途径；P21wAFl；Bax；细胞凋亡 IV Abstract ABSTRACT objeetive： To theeffectofthe ofHelicobacter investigate supematant priori(Hpylori) withdifferent onhuman ofceU genotypes gastricepithelialcells(GES—1)，thechanges and asthe ofP21 morphology，apoptosisprolifer