综合性医院3种肠道清洁剂的药物利用调查-中国现代应用药学.PDFVIP

·临 床· 综合性医院3 种肠道清洁剂的药物利用调查 胡豪，朱玲玲，徐领城，周权*(浙江大学医学院附属第二医院，杭州 310009) 摘要：目的 了解市售3 种聚乙二醇电解质型肠道清洁剂的药物利用情况。方法 利用浙江大学医学院附属第二医院HIS 系统，调查了3 种肠道清洁剂的临床医嘱或处方，进行数据挖掘。计算用药频度、日用金额等药物利用参数，应用最小 成本分析法进行药物经济学比较。结果 3 种肠道清洁剂临床使用疗效确切，患者服用后无明显的不耐受。恒康正清的 用药频度最高，是舒泰清与和爽用药频度的2 倍。和爽的给药最为方便，在配制灌洗液时无“漏掉小包”的缺陷，且日 用金额最低。结论 3 种肠道清洁剂中和爽最具有药物经济学价值。 关键词：肠道清洁剂；药物利用；药物经济学；最小成本分析法；每日限定剂量 中图分类号：R969.3 文献标志码：B 文章编号：1007-7693(2013)01-0197-03 Drug Utilization Study of Three Intestinal Cleaning Agents in a General Hospital * HU Hao, ZHU Lingling, XU Lingcheng, ZHOU Quan (Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China) ABSTRACT: OBJECTIVE To know the utilization status of three intestinal cleaning agents in clinical practice. METHODS Retrospective analysis of prescriptions with three intestinal cleaning agents was performed from hospital information system in our hospital. Data mining was conducted. Parameters of drug utilization study were calculated and pharmacoeconomic indices were compared by using cost minimization analysis. RESULTS The three drugs were effective without obvious intolerance in clinical use. The DDDs value of product Hengkang Zhengqing ranked first, twice the value of either Shutai Qing or Heshuang. Product Heshuang had the lowest risk of administration errors due to its “all in one” characteristics and also it had the lowest daily expenditure. CONCLUSION Product Heshuang is the most pharmacoeconomic intestinal cleaning agent. KEY WORDS: intestinal cleaning agents; drug utilization; pharmacoeconomics; cost minimization analysis; defined daily dose 肠道清理在结肠镜检查、治疗以及肠道手术前 院床位约2 200 床，门诊患者280 万/年) 。调查对 是必要的操作，它在防止术中污染、降低术后并 象为使用复方聚乙二醇电解质散型肠道清洁剂(恒 发症发生率及肠道功能恢复都起到重要的作用。 康正清﹑和爽和舒泰清) 的患者。恒康正清、和爽 口服肠道清洁剂在肠道清理中应用日益广泛。聚 和舒泰清分别由江西恒康药业、深圳万和制药