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Vaccines and Related Biological Products Advisory Committee (VRBPAC)May 21, 2002Prevnar?, Pneumococcal Conjugate Vaccine 7-valent, for the Prevention of Acute Otitis Media? R. Douglas Pratt, M.D., M.P.H. Review Team Jingyee Kou, Ph.D. Marion Gruber, Ph.D. Carl Frasch, Ph.D. Proposed Indication For active immunization of infants and toddlers against invasive disease and otitis media caused by Streptococcus pneumoniae due to capsular serotypes included in the vaccine (4, 6B, 9V, 14, 18C, 19F, 23F) Regulatory Background November 1999 February 2000 June 2000 May 2001 October 2001 March 2