血凝仪检测原理和应用.pptVIP

* 先天性凝血异常分析 * * 谢 谢！ 放映结束 感谢各位的批评指导！ 让我们共同进步 Both fibrinogen and fibrin are degraded by plasmin resulting in FDP’s. (fibrin or fibrinogen Degradation products.D-dimer is formed only from the breakdown of crosslinked fibrin. Therefore, D-Dimer is specific in that a clot must have been formed and then lysed. * Remember we are trying to diagnose clot formation or at least rule it out. D-Dimer is the only parameter that directly addresses both thrombin and plasmin generation hence it is more specific for DIC. A positive FDP could be a result of cleaved insoluble fibrin, fibrinogen or