托拉塞米在心衰治疗中的应用.pptVIP

托拉塞米(泽通)的作用位点 托拉塞米与其他袢利尿剂一样有微扩张血管作用 托拉塞米（泽通）抑制肾上腺素分泌醛固酮 Article Torsemide inhibits aldosterone secretion in vitro. Life Sciences (impact factor: 2.53). 02/1998; 63(3): PL45-50.DOI:10.1016/98)00265-3 ABSTRACT Torsemide inhibited aldosterone secretion by adrenal cells from rats, cows, and guinea pigs stimulated in vitro by potassium, angiotensin, dibutyryl cyclic AMP, ACTH, or corticosterone. Inhibitory concentrations for adrenal cells (micromolar) were comparable with those reported to inhibit ion transport in isolated renal tubules. Inhibition of a