羽叶鬼灯檠的化学成分及活性研究和两种生物活性筛选模型的应用研究.pdfVIP

摘 要 10µg/ml and 12.5µg/ml, respectively, in which two compounds 2001146 and 200111132 showed significant activities with IC50 at 0.30 and 0.37µg/ml, and extract 2001034 IC50 at 0.74µg/ml, respectively. Chapter 4 Progress in the Screening of Depigment Drugs Pigmentation is an important issue nowadays. In this chapter the progress of depigment drugs R D including melanogenesis pathway, methods in screening depigment drugs, class of depigment and tyrosinase inhibitors as well as their inhibitory mechanism were reviewed. Key words: Rodgersia pinnata, Saxifragaceae, Chemical Constituents, Active Constituents, Bioassay, Depigmentation, Tyrosinase, Anti-osteoporosis, Carbonic anhydrase II. V 羽叶鬼灯檠的化学成分及活性研究和两种生物活性筛选模型的应用研究 Compounds from Rodgersia pinnata Franch. RO O O OH O O OH OH OH CH3 OH HO OH OH OH OH 1* R = α-L-rhamnopyranosyl 2 R = α-L-arabinofuranosyl α-L-rhamnopyranosyl α-L-arabinofuranosyl RO O O OH O O OH OH OH OH OH OH OH OH 3 R = α-L-arabinofuranosyl 4 R = α-L-rhamnopyranosyl β-D-xylopyranosyl α-L-arabinopyranosyl 5 R = β-D-xylopyranosyl 6 R = α-L-arabino