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過敏性鼻炎的辨證施治及現代研究;过敏性鼻炎指南及诊疗标准
whiar.org; ARIA program
First phase:
Development of evidence-based guidelines during a workshop held at WHO in December 2019 (J Allergy Clin Immunol, suppl, Nov 2019).
Document has been endorsed by several allergy, respiratory, ENT and pediatric associations.
Second phase:
To produce materials to help improve delivery of care to those with rhinitis. In particular a pocket guide
To implement ARIA guidelines
To update the workshop report ; The ARIA initiative was developed
as a state-of-the-art for the specialist, the general practitioner and for health care workers:
to update their knowledge of allergic rhinitis,
to highlight the impact of allergic rhinitis on asthma,
to provide an evidence-based documented revision on the diagnosis methods,
to provide an evidence-based revision on the treatments available,
to propose a stepwise approach to the management of the disease,
to assess the magnitude of the problem in developing countries and to implement guidelines;Allergic rhinitis is a major chronic respiratory disease
Allergic rhinitis is associated with sinusitis and other co-morbidities such as conjunctivitis
Allergic rhinitis should be considered as a risk factor for asthma
A new subdivision of allergic rhinitis has been proposed:
Intermittent (IAR)
Persistent (PER)
The severity of allergic rhinitis has been classified as mild and moderate/severe“
A stepwise therapeutic approach has been proposed
The treatment of allergic rhinitis combines:
Allergen avoidance (when possible)
Pharmacotherapy
Immunotherapy
Education
Patients with persistent allergic rhinitis should be evaluated for asthma (10-40%)
Patients with asthma should be appropriately evaluated for rhinitis.(over 80%)
A combined strategy should be ideally used to treat the upper and lower airway diseases in terms of efficacy and safety.;变态反应、特应性、过敏性鼻炎的概念;变应性鼻炎的流行病学;病因;变应性鼻炎发病有两个阶段:
致敏阶段:当鼻黏膜接触到抗原(如花粉、霉菌、室尘等)后,经巨噬细胞吞噬处理,将抗原信息传递给免疫活性T、B淋巴细胞,在T淋巴细胞的辅助下,B淋巴细胞分裂增殖,转变
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