联合DTI与SWI在脑胶质瘤分级中的应用分析.pdfVIP

摘要 ④瘤体FA 值和ITSS分级并联筛检，敏感性为100%，特异性为78.6%。 max DTI SWI DTI SWI 结论：①高、低级别胶质瘤在 、 上有一定特征， 、 作为常 规MRI序列的补充，有助于胶质瘤分级。 ②DTI与SWI联合应用，能提高胶质瘤的分级诊断效能。 关键词：弥散张量成像；磁敏感加权成像；胶质瘤；受试者工作曲线 III Abstract ABSTRACT Objective:To evaluate the grading effectiveness of combined diffusion tensor imagingandsusceptibility-weightedimaginginpatientswithgliomas Materials and Methods:The MRI data of twenty-nine patients with histologically proved brain gliomas were retrospectively analyzed.According to the 2007 World Health Organization classification of tumours of the central nervous system,the patients were divided into high-grade group (15 cases) and low-grade group (14 cases).All patients were underwent MRI,enhanced MRI,DTI,and SWI before surgeon. We measured maximum fractional anisotropy values(FA ), ① max minimum fractional anisotropy values(FA ),mean fractional anisotropy values min (FA ), the range of fractional anisotropy values(FA ),minimum apparent mean range diffusion coefficient values(ADC ),mean apparent diffusion coefficient values min (ADC ) by placing ROIs within solid tumor components and measured FA mean mean values, ADCmean values by placing ROIs within peritumoral edema.Then using independent sample t-test analysised whether each parameter value of high- and low-grade group had statistical significant.A ROC curve was further applied to identify the optimal threshold of each parameter value