CRRT：严重脓毒症与MODS(邱海波)知识讲解.pptVIP

CRRT Severe sepsis and MODS;1. CRRT vs IRRT 2. Early vs late CRRT 3. High vs normal flow 4.Possible ways to increase mediators clearance ;Retrospective cohort study Pats with ARF and required dialysis between April 1,1996, and March 31, 1999 2 ICU in Canada. N=261;IHD vs CRRT;Munns et al观察危重急性肾衰竭患者 IHD CRRT CCr下降 25% 7% 尿量下降 50% 10% 钠排泄分数下降 46% 12% 肾功能下降的原因: IHD平均动脉压下降，导致肾脏低灌注，加重肾脏缺血性损伤，延迟急性肾衰竭肾功能的恢复 ;160 pats with ARF: Daily vs every-other-day IHD Mean ultrafiltration volume Daily: 1.2 ± 0.5 L Every-other-day: 3.5 ± 0.3 L (P 0.001). Hypotension occurred i