早期2型糖尿病患者血清Apelin水平与动脉粥样硬化的相关性研究.pdf

FINS、HOMA．承为自变量进行多元逐步回归分析，结果表明，在糖尿病患者(包 6．T2DM患者按照颈总动脉、髂总动脉、股动脉斑块有无分别分为2组，以有无 斑块作为因变量进行Logistic回归分析，结果显示，血清Apelin水平为影响早期 T2DM患者颈总动脉、髂总动脉、股动脉斑块的独立因素，具有统计学意义(P 0．05)。 的升高还与肥胖、胰岛素抵抗、脂代谢紊乱有关。2．早期T2DM动脉粥样硬化患 患者动脉粥样硬化发生的预报因子，Apelin可能是动脉粥样硬化的保护性因素。 关键词：2型糖尿病；动脉粥样硬化；Apelia 4 of 2diabetes oneofthemost leasonsof Or type mellitus(T2DM)is important disability in deathT2DM．A ofmechanismsinvolvedinitsocculTene2and variety development havenotbeen understood．Itisconfirmedthat isrelated process fully Apelin tosugar metabolismdisordersandinsulin resistance．So beinvolvedinthe Apdinmay ofincidenceand ofdiabeticmacrovascular processes development complication．This at the articleaims betweenserum leveland exploringrelationship Apelin atherosderosisin 2 toevaluatethe earlytype diabetes,and correlationin Apdin,bloodglucose,bloodpressure,blood lipids，blood resistanceindex and index c)，insulin hemoglobin(HbAl 0qOMa-ⅡUweight a1．This thebasisforfurtherresearchontheroleof (BMI)，et studymayprovide inatheroscleroticOCCUHenceand inT2DM． Apelin development MethodsInaccordancewith and recommendedofdiabetes diagnosis sub—type mellitusofWHOin 2diabetes