直肠癌伴同时性多发性肺转移患者的多学科临床决策探讨-中国肿瘤临床.PDFVIP

中国肿瘤临床2017年第44卷第19期 ChinJClinOncol2017.Vol.44.No.19 973 MDT论坛 · · 直肠癌伴同时性多发性肺转移患者的多学科临床决策探讨* ① ② ② ② ② ② ② 袁瑛 徐栋 杨琦 贝迪恺 刘月 张苏展 丁克峰 摘要 结直肠癌患者中肺是继肝脏之后最常见的远处转移器官之一，但由于肺转移发病率较低且生物学侵袭性相对温和，因而 与结直肠癌肝转移相比，结直肠癌肺转移无论是关注程度、综合治疗理念还是相关的临床和基础研究都相对匮乏。本文现介绍1 例直肠癌伴同时性多发性肺转移患者在浙江大学医学院附属第二医院大肠癌诊治中心的多学科综合治疗（multidisciplinary team，MDT）经过，以探讨该类患者的临床病理特征、预后影响因素、合理的综合治疗决策以及现有的诊治争议与共识，以期促进 临床诊疗的规范化和个体化，使患者更多获益。 关键词 直肠癌 肺转移 多学科讨论 临床完全缓解 观察等待 局部治疗 维持治疗 doi:10.3969/j.issn.1000-8179.2017.19.334 Multidisciplinary decision on a rectal cancer patient with multiple synchronous pulmo- nary metastasis 1 2 2 2 2 2 2 Ying YUAN , Dong XU , Qi YANG , Dikai BEI , Yue LIU , Suzhan ZHANG , Kefeng DING Correspondence to: Ying YUAN; E-mail: yuanying1999@ 1Department of Medical Oncology, 2 Department of Surgical Oncology, The Second Affiliated Hospital of Zhejiang University, School of Medicine, Hangzhou 310009, China This work was supported by National Natural Science Foundation of China (No., China National Health Industry Public Welfare Fund Project (No. 201402015), Natural Science Foundation of Zhejiang Province (No. LY14H160019), and National Sci- ence Technology Pillar Program during the Twelfth Five-year Plan Period (No. 2014BAI09B07) Abstract Lungs are the second most common distant metastatic organs of colorectal cancer, following the liver. However, clinical re- searches on lung metastasis are insufficient comparing with that on liver metastasis due to its low occurrence and relatively mild bio- logical behavior. This paper aims to investigate the clinicopathological characteristics and prognostic factors of rectal