抗生素合理使用教学案例.pptxVIP

急诊抗生素合理使用;主要内容;流行病学-严重感染;严重感染-发展趋势;感染的相关概念;ACCP/SCCM联席会议定义;;SIRS;SEPSIS;SEVERE SEPSIS;感染的演变过程;MODS的表现;Severe Sepsis 治疗;抗生素使用目标;Pharmacology of Antimicrobial Therapy;抗菌药物起效过程;Different pattern of time-killing of 3 Abx VS Pseudomonas;PK/PD Predictors of Efficacy;;依据PK/PD抗菌药物分类;Required %TMIC for cidal: ~ 40% for carbapenems ~ 50% for penicillins ~70% for ephalosporins;Drusano. Clin Infect Dis 2003;36(Suppl. 1):S42–S50;;Treatment of Multidrug-resistant Burkholderia cepacia With Prolonged Infusion Meropenem;Moore et al. J Infect Dis 1987;155:93–99;What is the Optimal AUIC for Fluoroquinolones?;Fo