围产期解脲脲原体感染和早产儿慢性肺部疾病.pptVIP

小结 妇女生殖道和孕期女性解脲脲原体感染高 妊娠期解脲脲原体感染将导致胚胎停育、反复自然流产胎膜早破、胎儿窘迫、早产、窒息 出生新生儿可发生先天性肺炎、血液、中枢感染、易发生慢性肺部疾病（BPD） 新生儿解脲脲原体感染早期有效的抗生素治疗可能有降低BPD的发生率 * * * * 持续定植或感染 positive specimens by culture or PCR throughout their hospitalization 早期暂时性定植或感染 at least 1 specimen positive by culture or PCR at 21 days of age with all subsequent specimens negative 晚期获得性感染 negative cultures and PCR specimens until day of age 21 with subsequent positive specimens Pediatrics 2002;110;45 Uu感染导致BPD的机理 Old BPD