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④division of truncus arteriosus and bulbus cordis ---right and left bulbar ridges: two spiral mesodermal ridges grow from the inner walls of the truncus arteriosus and bulbus cordis, twist around each other and fuse to form a spiral aortico-pulmonary septum ---bulbus arteriosus cordis and truncus arteriosus are divides into the aorta and the pulmonary trunk 3. Blood circulation of fetus and circulatory changes after birth 1) blood circulatio of fetus umbilical V→ducts venosus or hepatic sinus →inferior vena cava → right atrium →foramen ovale →left atrium →left ventricle →head and neck region →superior vena cava →right atrium→right ventrical → ductus arteriosus → aorta→gut and lower region of the body→umbilical A → placenta 2) circulatory changes after birth a.?umbilical V and ducts venousus: constrict and becomes into ligamentum teres hepatis and ligamentum venosus b.umbilical A: becomes into medial umbilical ligament, but proximal portion persist as superior vesical arteries c.?ductus arteriosus: constrict and become arterial ligament d.?foramen ovale closed 4. Congenital malformations 1) atrial septal defect: ---patency of the foramen ovale ---foramen secundum defect ---foramen primum effect ---endocardial cushion defect 2) ventricular septal defect: ---membranous part of the ventricular septum defect ---muscular part of the ventricular septum 3) abnormalities of the truncus arteriosus and bulbus arteriosus cordis ---unequal division of truncus arteriosus ---presistent truncus arteriosus ---transposition of the great vessels 4) tetralogy of Fallot: ---unequal division of truncus arteriosus ---four defects: /pulmonary stenosis /overriding aorta /membranous part fails to develop /hypertrophy of right ventricle 5) patent ductus arteriosus ? 组织胚胎学课件 七年制英文医学班专用 Chapter 27 Development of circulatory system Formation of primitive cardiovascular system 1) extra-embryonic blood vessels ---blood island: at the middle of 3rd week, wall of the yol
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