针灸与免疫功能在慢性前列腺炎慢性盆腔疼痛综合征中的随机对照研究档.docVIP

Complement Ther Med. Author manuscript; available in PMC 2015 Dec 1. Published in final edited form as: Complement Ther Med. 2014 Dec; 22(6): 965–969. Published online 2014 Oct 23.?doi:?? 10.1016/j.ctim.2014.10.010 PMCID:?PMC4254616 NIHMSID:?NIHMS640757 Acupuncture and Immune Function in Chronic Prostatitis/Chronic Pelvic Pain Syndrome: A Randomized, Controlled Study Shaun Wen Huey Lee, Ph.D,a? Men Long Liong, M.D.,b? Kah Hay Yuen, Ph.D,c?and? John N Krieger, M.D.d Author information??? Copyright and License information?? The publishers final edited version of this article is available at? Complement Ther Med Abstract \o Go to other sections in this page Go to: Introduction Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is common afflicting approximately 2% to 10% of men younger than 50 years of age 1?resulting in significant economic loss and reduced quality of life 2. CP/CPPS is characterized by perineal, lower abdominal, penile and ejaculatory pains, frequently accompanied by urinary symptoms and/or voiding dysfunction 3. Increasing evidence suggests that acupuncture could benefit men with CP/CPPS 4,? 5. Our group recently showed that acupuncture was a promising treatment for patients with CP/CPPS 6, with nearly twice as many CP/CPPS patients responding to acupuncture treatment than to sham acupuncture. CP/CPPS has been associated with increased auto-reactive T cells? 7,? 8. In a recent animal study, Quick and colleagues demonstrated that transfer of T cells, and more specifically CD4+?T cells, could mediate development of pelvic pain in mice 8. Based on these studies, we investigated the possibility that acupuncture may affect the immune system in patients with CP/CPPS and whether these changes might correlate with clinical response to treatment. \o Go to other sections in this page Go to: Methods Study setting and procedures This was part of a larger, randomised controlled clinical trial that has been published 6,? 9.