非活動期sle合併妊娠の臨床統計学的考察.pdfVIP

産 婦進 歩 第37巻2・3号(合 併号) 1985.7.(pp.111～116) 111-41 臨 床 研 究 III 非活 動期SLE合 併妊 娠 の臨床統 計学 的考察 大阪市立大学医学部産科婦人科学教室(主任:須川 倍教授) 川端 政實 ・梅咲 直彦 ・朝 田 拓治 ・大鹿 幸信 迫 久男 ・駒谷美津男 ・須川 倍 (1985年2月27日受付) Statistical Study of the Outcome for Mother and Fetus in Pregnancy with Inactive SLE MasamiKAWABATA,NaohikoUMESAKI,TakujiASADA,YukinobuOSHIKA, HisaoSAKO,MitsuoKOMATANIandTadashiSUGAWA Department of Obstetrics and Gynecology, Osaka City University, Osaka (Director: Prof. Tadashi Sugawa) Recently, the prognosis of patients with SLE has remarkably improved and the number of patients with inactive SLE who become pregnant has increased. We experienced pregnancies with inactive SLE during a seven year period, and we analyzed them statistically regarding the outcome of mother and fetus in comparison with the active SLE pregnancies and normal pregnancies. In all 9 cases, the SLE had already been diagnosed and was clinically stable at the time of conception. Eight of 9 inactive SLE pregnant women, were being administrated various doses of prednisolone for the management of the SLE. In all nine cases the SLE was not aggreva- ted and severe renal exacerbation wasnt found throughout the pregnancy, but in 2 cases fever and arthritis occurred after parturition. The complement level and levels of complement component C 3 and C 4 were not remarkably different from in normal pregnancy. S