分子生物物理学.pptVIP

Sheet 20-28% (Kabsch Sander, 1983; Creighton, 1993) Turn that serve to reverse the direction of the polypeptide chain Surface of the protein Antibody recognition, phosphorylation, glycosylation, hydroxylation Identification of secondary structure Distortions of a-helices The majority of a-helices in globular proteins are curved or distorted somewhat compared with the standard Pauling-Corey model. Why? The packing of buried helices against other secondary structure elements in the core of the protein Proline residues induce distortions of around 20 degrees in the direction of the helix a