Consensus and Update on the Definition of On-Treatment Platelet Reactivity to Adenosine Diphosphate Associated With Ischemia and Bleeding血小板对二磷酸腺苷与缺血出血相关反应定义的共识和最新进展.pdf

Journal of the American College of Cardiology Vol. 62, No. 24, 2013 2013 by the American College of Cardiology Foundation ISSN 0735-1097/$36.00 Published by Elsevier Inc. /10.1016/j.jacc.2013.07.101 STATE-OF-THE-ART PAPER Consensus and Update on the Definition of On-Treatment Platelet Reactivity to Adenosine Diphosphate Associated With Ischemia and Bleeding Udaya S. Tantry, PHD,* Laurent Bonello, MD, PHD,y Daniel Aradi, MD, PHD,z Matthew J. Price, MD,x Young-Hoon Jeong, MD, PHD, k Dominick J. Angiolillo, MD, PHD,{ Gregg W. Stone, MD,# Nick Curzen, BM (HONS), PHD,** Tobias Geisler, MD,yy Jurrien ten Berg, MD, P HD,zz Ajay Kirtane, MD, SM,# Jolanta Siller-Matula, MD, P HD,xx Elisabeth Mahla, MD,kk Richard C. Becker, MD,{{ Deepak L. Bhatt, MD, MPH,## Ron Waksman, MD,*** Sunil V. Rao, MD,yyy Dimitrios Alexopoulos, MD,zzz Rossella Marcucci, MD, PHD,xxx Jean-Luc Reny, MD, P HD, kkk Dietmar Trenk, PHD,{{{ Dirk Sibbing, MD,### Paul A. Gurbel, MD,* for the Working Group on On-Treatment Platelet Reactivity Baltimore, Maryland; Marseille, France; Balatonfüred, Hungary; La Jolla, California; Jinju, South Korea; Jacksonville, Florida; New York, New York; Southampton, United Kingdom; Tübingen, Bad Krozingen, and Munich, Germany; Vienna and Graz, Austria; Durham, North Carolina; Boston, Massachusetts; Washington, DC; Patras, Greece; Florence, Italy; and Geneva, Switzerland Dual antiplatelet therapy with aspirin and a P2Y12 receptor blocker is a key strategy to reduce platelet reactivity and to prevent thrombotic events in patients treated with percutaneous corona