NASIDs相关胃肠道损伤PPI应用.pptVIP

* * As we reviewed earlier, low-dose ASA even by itself can be problematic in high-risk patents. 正如我们以前所说，对于高危患者来说小剂量的ASA本身就是一个问题。 Lai and colleagues in 2002 reported a study of a group of patients hospitalized because of complicated ulcer disease (mainly bleeding) and who had been taking aspirin at a dose of only 100 mg per day. All patients were H. pylori positive. The ulcers were healed by treating the H. pylori infection. After ulcer healing and treatment of H. pylori infection, aspirin therapy was re-initiated and patients were also randomized to a PPI, lansoprazole 30 mg daily, or to