超敏反应讲解.pptxVIP

Hypersensitive Reactions超敏反应讲解人:杨自飞指导老师:林影 教授 The ability of the immune system to respond inappropriately to antigenic challenge was recognized early in last century. Two French scientists, Paul Portier and Charles Richet anaphylaxis(过敏性反应) Richet was subsequently awarded the Nobel Prize in Physiology or Medicine in 1913 for his work on anaphylaxis.消除AgAg免疫应答组织损伤、生理功能改变超敏反应变态反应过敏反应Hypersensitivity allergy anaphylaxis超敏反应定义超敏反应是指已致敏的机体再次接触相同抗原时所发生的生理功能紊乱和（或）组织细胞损伤。超敏反应的分类Gell and Coombs Classification I 型超敏反应速发型Ⅱ型超敏反应 细胞毒型或细胞溶解型Ⅲ型超敏反应 免疫复合物型或 血管炎型Ⅳ型超敏反应 迟发型I 型 超 敏 反 应IgE-Medi