医学07抗体分子抗体基因重排及B细胞发育.pptVIP

Heavy chain diversity created by variable recombination A A T A G A G A T A G A G A T G A G G C G T A C A C T G G T G T A A T A C A C T G G T G T A A G A C A C T G G T G T A A A C C T G G T G T A C C G T G T A C G T G A C G T T T G T A C C C Asp Arg Arg Arg Asn Asp Asp Asp Tyr Tyr Try Try Try Gly Gly Gly Asn Ser Ser Tyr Tyr Trp Trp Gly Ser Tyr Phe Tyr Ser Thr J H V H D S107 M603 M167 S107 M603 M167 Light chain diversity created by variable recombination C C C C C C T G G C C C T G G Pro Trp Protein Recombined DNA Germ line DNA C C C C C C T G G C C C