年产6000万盒复方赖氨酸颗粒（规格3g10袋盒）的车间工艺设计.docVIP

毕业设计(论文) 题 目 年产6000万盒复方赖氨酸颗粒 （规格3g*10袋/盒）的车间工艺设计 学院名称 化学化工学院 指导教师 职 称 副教授 班 级 制药工程112班 学 号 学生姓名 2015年 6 月 7 日 年产6000万盒复方赖氨酸颗粒（规格3g*10袋/盒）的车间工艺设计 摘要：赖氨酸是一种α-氨基酸，它的化学式为HOOCCH(NH2)(CH2)4NH2，是人体八大必需氨基酸之一，必须通过日常饮食和营养补品获得。作为一种氨基酸，它是肉碱生产合成的一个重要组成部分，肉碱负责将一些不饱和脂肪酸转化为能量，有助于降低胆固醇水平。赖氨酸属于碱性氨基酸，能增强免疫功能、促进人体发育，并且有提高中枢神经组织功能的作用。它可以和其他氨基酸一起形成胶原蛋白，胶原蛋白在结缔组织，肌肉，肌腱，骨骼和关节软骨中扮演了重要角色。国内外研究表明，该药起效迅速，不良反应少，发展前景广阔。复方赖氨酸颗粒，其生产工艺符合颗粒剂的生产工艺，工艺流程主要有原辅料的粉碎与筛分，混合，制粒，干燥，整粒，包装等步骤。本设计对所选择的工艺路线进行了物料衡算，并对主要设备进行了选型和计算，设计出完整的车间平面布置图。该工艺简单、经济，车间布局合理，符合GMP要求。 关键词：复方赖氨酸 颗粒剂 生产工艺 车间平面布置图 An annual output of 60 million boxes Compound Lysine Granules(specification 3g * 10 bags / box) process design workshop Abstract : Lysine is an α-amino acid，It`s chemical formula is HOOCCH(NH2) -(CH2)4NH2，is one of the eight essential amino acids, must be obtained through diet and nutritional supplements.As an amino acid, which is an important part of the production of the synthesis of carnitine, carnitine is responsible for some of the unsaturated fatty acids into energy, it helps to reduce cholesterol levels. Lysine belong to the basic amino acids, can enhance immune function, promote human development, and central nervous system has been improved function. It can and other amino acids together to form collagen, collagen plays an important role in connective tissue, muscles, tendons, bones and cartilage in the joints. Research has shown that the drug has a rapid onset, fewer side effects and broad development prospects. Compound Lysine Granules, its production process in line with the production process granules, the process of the main raw materials crushing and screening, mixing, granulating, drying, whole, packaging and other steps. The design of the selected process route was material balance, and the main equipment for the selection and calculation, design