发育生物学胚胎发育信号传导途径.pptVIP

发育中的信号传导 产题的Q复 邮飞间  CELL COMMUNICATION Plasma membra 细胞通讯:一个细胞发 isassembly) AFLcAMP-Kinasel 出的信息通过介质传递 到另一个细胞,并使之 Endoplasmic 产生相应的反应。 glycogen breakdo DNA synthesis t RNA synthesis  CELL COMMUNICATION Plasma membra 细胞间通讯在胚胎发 isassembly) AFLcAMP-Kinasel 育中起关键作用。 ●细胞本身的分化命运 Erm也受到周围细胞的影响 ●信号传导是细胞间通 讯的主要形式。 glycogen breakdo DNA synthesis t RNA synthesis  信号传导 FIGAMP-LKinase glyceride -Kinase alcoa ormation t RNA synthesis ●信号传导:由信号细胞产生信号分子 signaling molecular)诱 导靶细胞( target cel发生某种效应。靶细胞通常通过特异性受体 识别细胞外信号分子,并把细胞外信号转变为细胞内信号,引起细 胞发生反应,这一过程称为信号传导( signal transduction)  Embryogenesis is controlled by surprisingly few signal transduction pathways: 1) TGFB/BMP Serine/Threonine kinase receptors 2) Receptor Tyrosine kinases such as FGF, EGF, IGF Insulin 3) Wnts 4)Sonic Hedgehog 5)Notch 6) Nuclear hormone receptors Only a few signaling pathways pattern the embryo, but there are hundreds of differentiated cell types in the human body. The same signals can trigger different types of cell differentiation responses in cells of different developmental history.