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474 III Pd-CATALYZED CROSS-COUPLING
D.ii.d. Alkylation
3
Tin Reagents. In stannanes sp -hybridized carbon attached directly to the metal is less
2
reactive than sp - or sp-hybridized carbon in the transfer process to the Pd(II) intermediate
in the catalytic cycle. Tetramethyl- or tetrabutylstannane can be used for the preparation of
methyl and but
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