monitoring protein synthesis in single live cancer cells.[2016][integrative biology quantitative biosciences from nano t.监控单活肿瘤细胞内蛋白质的合成。[2016][综合生物学定量英文精品课件.pdf

Integrative Biology TECHNICAL INNOVATION View Article Online View Journal | View Issue . 0 1 : 5 2 : Monitoring protein synthesis in single live cancer 6 0 7 1 cells† 0 2 Cite this: Integr. Biol., 2016, / 1 0 8, 645 a bc bc bc d / Chengyi Tu, Loredana Santo, Yuko Mishima, Noopur Raje, Zeev Smilansky 3 2 a n and Janet Zoldan* o Y R A R Protein synthesis is generally under sophisticated and dynamic regulation to meet the ever-changing B I demands of a cell. Global up or down-regulation of protein synthesis and the shift of protein synthesis L Y location (as shown, for example, during cellular stress or viral infection) are recognized as cellular T I S responses to environmental changes such as nutrient/oxygen deprivation or to alterations such as R E pathological mutations in cancer cells. Monitoring protein synthesis in single live cells can be a powerful V I N tool for cancer resear