9黏膜免疫 研究生.pptVIP

Capture of antigens from the intestinal lumen by mononuclear cells in the lamina propria . First panel: soluble antigens such as food proteins might be transported directly across or between enterocytes, or there might be M cells in the surface epithelium outside Peyers patches. Second panel: enterocytes can capture and internalize antigen:antibody complexes by means of the FeRn on their surface and transport them across the epithelium by transcytosis. At the basal face of the epithelium, lamina propria dendritic cells expressing FeRn and other Fe receptors pick up and internalize the comp