诺贝尔专题课件.pptVIP

The 2009 Nobel prize special topic;Part Ⅰ：The secret of agelessness;The?2009?Nobel?Prize?in?Physiology?or?Medicine?is?awarded?to? Drs.?Elizabeth?H?Blackburn,?Jack?W?Szostak?and?Carol?W?Greider?for?their?discovery?of?how?chromosomes?are?protected?by?telomeres?and?the?enzyme?telomerase.;Figure?1.?The?end‐replication?problem;the?stage?for?the?discoveries;;;Figure?2? The?DNA?end‐sequence?of?linear?DNA?molecules?from?Tetrahymena?added?to?artificial?minichromosomes?allows?their?longterm?stable?maintenance? in?yeast.;;;;Figure?3.?Model?for?elongation?of?telomeres?by?telomerase.;Significance?of?the