生物化学课件：2 Biosynthesis of amino acids and related molecules.pptVIP

Biosynthesis of amino acids and related molecules氨基酸及其衍生物的生物合成 Contents Overview of nitrogen metabolism Reduction (fixation) of N2 into ammonia (NH3 or NH4+) Synthesis of the 20 amino acids Synthesis of other biomolecules from amino acids 2. Nitrogen is fixed by enzymes of the nitrogenase complex Nitrogen fixation: Conversion of N2 to NH3 in diazotrophs (固氮生物) Cyanobacteria (蓝绿藻, photosynthetic) rhizobia (根瘤菌, symbiont 共生生物 ) Ammonia is incorporated into biomolecules through glutamate and glutamine First, glutamine synthetase (Gln 合成酶) catalyzed the reaction of glutamate and NH4+ to