先天性甲状腺功能减低症4.pptVIP

PEDIATRICS 先天性甲状腺功能减低症 CongenitalHypothyroidism introduction ? name-----previously called cretinism,now it is discarded ? Concept----Hypothyroidism results from deficient production of thyroid hormone or defect in its receptor. The characteristics is low metabolism level and retardation in growth and mental development. etiology 1. errors in embryologic development of thyroid 2. congenital defect of thyroid function 1) defective synthesis of thyroxine 2) 2) poor responsiveness of TSH 3) 3. congenital defect of hypothalamus and pituit