控制昼夜节律的分子机制.pptxVIP

First, two questions.;The biological clock is warning you;The sunset but the rest. （日落而息）;HOW DOES IT WORK IN GENE?; The fruit fly : sleeps during the day howls during the night ;How to Realize Regulation of Circadian Rhythm precisly? 如何实现昼夜节律的精确调控?;The period gene encodes a protein called PER. The timeless gene encodes a protein called TIM. The double-time gene encodes a protein called DBT. ;The PER protein will be transferred from the cytoplasm(细胞质) to the nucleus with the help of TIM protein at night. The PER protein will degrade（降解） during the day. The process of accumulation and degrad