可比特与布地奈德雾化吸入对小儿肺炎的疗效观察.docxVIP

可比特与布地奈德雾化吸入对小儿肺炎的疗效观察 【摘要】目的：研究可比特与布地奈德雾化吸入对小儿肺炎的疗效观察。 方法： 研究对象选取我院2014年6月到2016年4月间门诊小儿肺炎患者100例，采用 随机数字法将其分为对照组和观察组， 每组各50例。两组患儿均采取常规治疗， 对照组患儿给予可比特治疗治疗，观察组患者采用布地奈德联合可比特治疗。 比较两组患者的治疗总有效率、两组患儿症状消失时间、治疗前后白细胞 （WBC）、中性粒细胞百分比（Neu%）及C反应蛋白（CRP）水平和不良反应 发生率。结果：观察组的治疗总有效率96.00%，明显高于对照组 2 （80.00%）（ x=4.64,P=0.03）;观察组的临床症状消失时间长于对照 （P0.05）;治疗 后观察组的 WBC及CRP水平低于对照组（PV0.05）;观察组不良反应发生率10%， 明显低于对照组18%（X=4.33,P=0.03）。结论：布地奈德联合可比特治疗小儿肺炎 临床疗效显著，能够明显改善炎症反应，缓解患儿咳嗽、喘促、高热症状，缩短 治疗时间，值得在临床推广。 【关键词】可比特；布地奈德；小儿肺炎；临床疗效 Efficacy of nebulized inhalation of Compound ipratropium bromide and budesonide in children with pneumonia ABSTRACT Objective:To study the Efficacy of nebulized in halation of Compound ipratropium bromide and budesonide in children with pneumonia. Methods:The subjects were 100 children with pneumonia in our hospital from June 2014 to April 2016, ran domly divided into con trol group and observati on group, 50 cases in each group.The two groups were treated with conven ti onal treatme nt, while the con trol group was treated with Compo und ipratropium bromide. The observati on group was treated with budesonide combined with Compound ipratropium bromide.Compare the total effective rate of the two groups of patie nts, Compare time of symptom disappeara nee of two groups ,Compare WBC and CRP levels of the two groups before and after treatme nt, Compare childre n with adverse reacti ons rate of two groups. Results:The total effective rate of the observatio n group was 96%, which 2 was significantly higher than that of the control group (80%) ( x =4.64, P=0.03);The cli nical symptom disappeara nee time of the observati on group was Ion ger tha n that of the control (P0.05); after 1 weeks treatment, the WBC and CRP levels of the observation group were lower than that of the control group (P0.05); the incidence of adverse reacti ons of the observati on group was 10%,which was sig nifica ntly lower 2 than that of the control group (18%) (x =4.16, P=0.04).Conclusion: The clinical efficacy o