罗红霉素含量的荷移光谱法测定(精).docxVIP

罗红霉素含量的荷移光谱法测定 【关键词】 罗红霉素 7 7 8 8? 菜那杌 ?对二次甲基苯醌 荷移反应 分光光度法 Spectrophotometric determination of roxithromycin ABSTRACT The charge transfer interactions between roxithromycin and 7,7,8,8??tetracyanoquinodimethane (TCNQ) were investigated by spectrophotometry. The apparent molar absorptivity of TCNQ complex is 1.57 ×104 L/(mol?cm) at 743nm, and 2.93 ×104 L/(mol?cm) at 844 nm; the result obeys Beers law in the concentration range of 0 ～55 mg/L. The relative standard deviation of the method is 1.0% (n=6). The composition of complex of roxithromycin with 7,7,8,8??tetracyanoquinodimethane is 1 ∶2. T