素注射治疗婴儿血管瘤临床对比研究魏.docVIP

A群链球菌制剂、平阳霉素联合强的松龙注射治疗 体表血管瘤和脉管畸形的临床对照研究 魏海刚邱雅陈玉婷李蜀光 1广东省佛山市第二人民医院口腔颌面外科528000 【摘要】目的 前瞻性观察并评价A群链球菌制剂和平阳霉索注射治疗颌面部血管瘤、 静脉畸形和淋巴管畸形的治疗效果。方法 选取门诊及住院颌而部脉管瘤120例，随机分组 采用A族链球菌制剂和平阳霉素注射治疗，对所有病例进行随访,并记录其疗效及毒副作用。 结果 血管瘤36例,A群链球菌制剂组15例，治愈8例(53. 33% );平阳每素组21例，治愈 12例(57. 14% ) o静脉畸形40例,A族链球菌制剂治疗组19例，治愈13例(6 42%);平阳 霉索组21例，治愈14例(66. 67% ) o淋巴管畸形44例,A族链球菌制剂治疗21例，治愈14 例(66. 67% );平阳霉素治疗23例，治愈6例(26. 09% )。结论A族链球菌制剂注射治疗淋 巴管畸形效果更为明显，八族链球菌制剂和平阳每素注射治疗血管瘤和静脉畸形均有效。 【关键词】血管瘤；静脉畸形；淋巴管畸形；A族链球菌制剂；平阳霉素 作者简介：魏海刚男37岁医学硕士副主任医师课题负责人 通讯作者：李蜀光男47岁医学博士主任医师研究方向；口腔颌而整形 (基金项目：佛山市科技局医学专项基金立项，立项编号：200908080) Comparison between Streptococcus A group preparation for injection andpingyangmycin in treatment of body surface hemangiomas and vascularmalformation Wei haigang1 Qiu ya1 Chen yuting1 Li shuguang1 1 Foshan Second People s Hospital, Guangdong 528000 【Abstract ] Objective To evaluate and compare the efficacy of Streptococcus A group preparation for injection and pingyangmycin in treatment of body surface hemangiomas, venous malformation and lymphatic malformation. Methods 120 patients with body surface vascular tumors were randomly divided into two groups, one group was given streptococcus A group preparation for injection, and the other group was given pingyangmycin. The therapeutic efficacy was recorded and the patients were followed up for one to five years? Results In 36 hemangioma patients, the effective rate of streptococcus A group preparation for injection was 53.33% , the effective rate of pingyangmycin was 57.14%. In 40 venous malfonnation patients, the effective rate of streptococcus A group preparation for injection was 68.42%、and the effective rate of pingyangmycin was 66.67%? In 44 lymphatic malformation cases, the effective rate of streptococcus A group preparation for injection was 66.67% which was obviously higher than the effective rate of pingyangmycin 26.09%. Conclusion The efficacy of Streptococcus A group preparation for injection in treatment of lymphatic malformation is better